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Medical symptoms and causes for MUSCLE WEAKNESS
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Symptom: MUSCLE WEAKNESSCause: Immobility
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Description:
Immobilization in a cast, a splint, or traction can lead to MUSCLE WEAKNESS in the involved extremity; prolonged bed rest or inactivity results in generalized MUSCLE WEAKNESS



Symptom: MUSCLE WEAKNESSCause: Spinal trauma and disease
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Description:
Trauma can cause severe MUSCLE WEAKNESS, leading to flaccidity or spasticity and, eventually, paralysis. Infection, tumor, and cervical spondylosis or stenosis can also cause MUSCLE WEAKNESS


Symptom: MUSCLE SPASMS (Muscle cramps)Cause: Amyotrophic lateral sclerosis (ALS)
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Description:
With ALS, MUSCLE spasms may accompany progressive MUSCLE WEAKNESS and atrophy that typically begin in one hand, spread to the arm, and then spread to the other hand and arm. Eventually, MUSCLE WEAKNESS and atrophy affect the trunk, neck, tongue, larynx, pharynx, and legs; progressive respiratory MUSCLE WEAKNESS leads to respiratory insufficiency. Other findings include MUSCLE flaccidity progressing to spasticity, coarse fasciculations, hyperactive deep tendon reflexes (DTRs), dysphagia, impaired speech, excessive drooling, and depression


Symptom: MUSCLE ATROPHY (Muscle wasting)Cause: Amyotrophic lateral sclerosis (ALS)
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Description:
Initial symptoms of ALS include MUSCLE WEAKNESS and atrophy that typically begin in one hand, spread to the arm, and then develop in the other hand and arm. Eventually, WEAKNESS and atrophy spread to the trunk, neck, tongue, larynx, pharynx, and legs; progressive respiratory MUSCLE WEAKNESS leads to respiratory insufficiency. Other findings include MUSCLE flaccidity, fasciculations, hyperactive DTRs, slight leg MUSCLE spasticity, dysphagia, impaired speech, excessive drooling, and depression


Symptom: MUSCLE WEAKNESSCause: Drugs
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Description:
Generalized MUSCLE WEAKNESS can result from prolonged corticosteroid use, digoxin, and excessive doses of dantrolene. Aminoglycoside antibiotics may worsen WEAKNESS in patients with myasthenia gravis



Symptom: MUSCLE WEAKNESSCause: Amyotrophic lateral sclerosis (ALS)
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Description:
ALS typically begins with MUSCLE WEAKNESS and atrophy in one hand that rapidly spread to the arm and then to the other hand and arm. Eventually, these effects spread to the trunk, neck, tongue, larynx, pharynx, and legs; progressive respiratory MUSCLE WEAKNESS leads to respiratory insufficiency


Symptom: RESPIRATIONS, SHALLOWCause: Amyotrophic lateral sclerosis (ALS)
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Description:
Respiratory MUSCLE WEAKNESS in ALS causes progressive shallow respirations. Exertion may result in increased WEAKNESS and respiratory distress. ALS initially produces upper extremity MUSCLE WEAKNESS and wasting, which in several years affect the trunk, neck, tongue, and MUSCLEs of the larynx, pharynx, and lower extremities. Associated signs and symptoms include MUSCLE cramps and atrophy, hyperreflexia, slight spasticity of the legs, coarse fasciculations of the affected MUSCLE, impaired speech, and difficulty chewing and swallowing


Symptom: MUSCLE FLACCIDITY (Muscle hypotonicity)Cause: Amyotrophic lateral sclerosis
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Description:
Progressive MUSCLE WEAKNESS and paralysis are accompanied by generalized flaccidity. Typically, these effects begin in one hand, spread to the arm, and then develop in the other hand and arm. Eventually, they spread to the trunk, neck, tongue, larynx, pharynx, and legs; progressive respiratory MUSCLE WEAKNESS leads to respiratory insufficiency. Other findings include MUSCLE cramps and coarse fasciculations, hyperactive DTRs, slight leg MUSCLE spasticity, dysphagia, dysarthria, excessive drooling, and depression



Symptom: MUSCLE WEAKNESSCause: Seizure disorder
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Description:
Temporary generalized MUSCLE WEAKNESS may occur after a generalized tonic-clonic seizure; other postictal findings include a headache, MUSCLE soreness, and profound fatigue


Symptom: MUSCLE WEAKNESSCause: Myasthenia gravis
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Description:
Gradually progressive skeletal MUSCLE WEAKNESS and fatigue are the cardinal symptoms of myasthenia gravis. Typically, WEAKNESS is mild upon awakening, but worsens during the day. Early signs include weak eye closure, ptosis, and diplopia; blank, masklike facies; difficulty chewing and swallowing; nasal regurgitation of fluid with hypernasality; and a hanging jaw and bobbing head. Respiratory MUSCLE involvement may eventually lead to respiratory failure
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