Medical term:
PTEN
PTEN
A gene on chromosome 10q23.3 which encodes PTEN (phosphatase and tensin homolog), a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase protein, which acts as a tumour suppressor by negatively regulating the AKT/PKB-signalling pathway.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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