Medical term:
Thromboxane
thromboxane
[throm-bok´sān]an intermediate in the metabolic pathway of arachidonic acid, formed from prostaglandin endoperoxides, and released from suitably stimulated platelets; the unstable form, thromboxane A2, is a potent inducer of platelet aggregation and constrictor of arterial smooth muscle.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
throm·box·ane
(throm-bok'sān),The formal parent of the thromboxanes; prostanoic acid in which the -COOH has been reduced to -CH3 and an oxygen atom has been inserted between carbons 11 and 12.
Farlex Partner Medical Dictionary © Farlex 2012
thromboxane
(thrŏm-bŏk′sān)n.
Any of several compounds, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
throm·box·anes
(throm-boks'ānz),A group of compounds, included in the eicosanoids, formally based on thromboxane, but with the terminal COOH group present; biochemically related to the prostaglandins and formed from them through a series of steps involving the formation of an endoperoxide (an O-O bridge between carbons 9 and 11 in the prostaglandins) by a cyclooxygenase, followed by a rearrangement (catalyzed by thromboxane synthase) that inserts one of the two oxygen atoms between carbons 11 and 12, leaving the other still bridging carbons 9 and 11. Thromboxanes are so named from their influence on platelet aggregation and the formation of the oxygen-containing six-membered ring (pyran or oxane). Like the prostaglandins, individual thromboxanes (abbreviated TX) are designated by letters (A, B, C, etc.) and subscripts indicating structural features.
Farlex Partner Medical Dictionary © Farlex 2012
throm·box·anes
(throm-bok'sānz)A group of compounds, included in the eicosanoids, formally based on thromboxane, but with the terminal COOH group present; biochemically related to the prostaglandins and formed from them. Thromboxanes are so named from their influence on platelet aggregation and the formation of the oxygen-containing six-membered ring (pyran or oxane). Like the prostaglandins, individual thromboxanes (abbreviated TX) are designated by letters (A, B, C, and onward) and subscripts indicating structural features.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
thromboxanes
Substances similar to the prostaglandins that promote blood clotting. Aspirin in small doses reduces the production of thromboxane by PLATELETS.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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