Medical term:
acanthocytes
a·can·tho·cyte
(ă-kan'thō-sīt),An erythrocyte characterized by multiple spiny cytoplasmic projections, as in acanthocytosis.
[acantho- + G. kytos, cell]
Farlex Partner Medical Dictionary © Farlex 2012
Acanthocyte
A densely stained spheroidal red cell with multiple (usually 5–12), irregularly distributed, thorn-like spicules of variable size, often with drumstick ends.Aetiology Hereditary abetalipoproteinemia* (hereditary acanthocytosis), severe (end stage) liver disease, hepatorenal failure, anorexia nervosa, chronic starvation. A small number of acanthocytes may be seen in severe haemolytic anaemia, especially post splenectomy, haemolytic anaemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration, and rarely also in otherwise normal blood smears (one or two per smear), where they correspond to older, effete red cells approaching their “expiration” date of 120 days.
*Accompanied by decreased total serum lipids, phospholipids, cholesterol, vitamin E, vitamin A
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
acanthocyte
Acanthrocyte Hematology An RBC with a irregularly spaced, pointed spicules, of varying shape and number–Greek, ακαντηο, spike; acanthocytes are seen in abetalipoproteinemia–hereditary acanthocytosis, as well as in alcoholic cirrhosis with hemolytic anemia, hemolytic anemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration or splenectomy. See Red blood cells.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
a·can·tho·cyte
(ă-kan'thō-sīt)An erythrocyte characterized by spiny cytoplasmic projections.
[acantho- + G. kytos, cell]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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