Medical term:
autoantibody
autoantibody
[aw″to-an´tĭ-bod″e]an antibody formed in response to, and reacting against, an antigenic constituent of the individual's own tissues.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
au·to·an·ti·bod·y
(aw'tō-an'ti-bod-ē),An antibody that occurs in response to antigenic constituents of the host's tissue (or "self antigen") and reacts with the inciting target tissue.
Farlex Partner Medical Dictionary © Farlex 2012
autoantibody
(ô′tō-ăn′tĭ-bŏd′ē)n.
An antibody that reacts with the cells, tissues, or native proteins of the individual in which it is produced.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
autoantibody
Any antibody produced by an organism against one of its own—self-antigens.Autoantibodies
Examples of autoantibodies and disease associations
• Anti-actin antibodies—coeliac disease.
• Anti-centromere antibodies—CREST syndrome.
• Anti-ganglioside antibodies—acute motor neuronal neuropathy.
• Antimitochondrial antibody—primary biliary cirrhosis.
• Anti-neutrophil cytoplasmic antibody—Wegener’s granulomatosis (in neutrophil cytoplasm).
• Anti-neutrophil cytoplasmic antibody—Churg-Strauss syndrome, microscopic polyangiitis, systemic vasculitides (perinuclear location).
• Anti-nuclear antibodies (e.g., anti-SSA/Ro)—systemic lupus erythematosus.
• Anti-signal recognition peptide—polymyositis.
• Anti-smooth muscle antibody—chronic autoimmune hepatitis.
• Anti-glomerular basement membrane antibodies.
• Anti-parietal cell antibodies, and others.
• Anti-nuclear antibodies (ANA).
• Anti-smooth muscle actin (SMA).
• Anti-liver-kidney-microsomal antibody (LKM), 2 types:
- Anti-mitochondrial (AMA);
- Perinuclear antineutrophil cytoplasmic (pANCA).
• Anti-soluble liver antigen (SLA), other autoantibodies.
• ANA and SMAs are known to be positive in AIH, PBC, PSC, HCV, HBV, HDV, NASH, drug-induced hepatitis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
autoantibody
Immunology Any antibody produced by an organism against one of its own–self antigens. See Antibody, Hashimoto's thyroiditis, Lupus erythematosus, Myasthenia gravis, Rheumatoid arthritis.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
au·to·an·ti·body
(aw'tō-an'ti-bod-ē)Antibody occurring in response to antigenic constituents of the host's tissue, and which reacts with the inciting tissue component.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
autoantibody
An antibody derived from the immune system, which then acts against body tissues or constituents.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Autoantibody
An antibody produced by the body in reaction to any of its own cells or cell products.
Mentioned in: Antimyocardial Antibody Test, Antinuclear Antibody Test, Autoimmune Disorders, Cold Agglutinins Test, Myasthenia Gravis
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
au·to·an·ti·body
(aw'tō-an'ti-bod-ē)Antibody occurring in response to antigenic constituents of the host's tissue, and which reacts with the inciting tissue component.
Medical Dictionary for the Dental Professions © Farlex 2012
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