Medical term:
nCk
NCK1
A gene on chromosome 3q21 that encodes an adapter protein which associates with tyrosine-phosphorylated growth factor receptors (e.g., KDR and PDGFRB) or their substrates. NCK1 maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. It plays a role in DNA damage response by activating downstream effectors, such as that of CHEK2, and in ELK1-dependenttranscriptional activation in response to activated Ras signalling.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Latest Searches:
alipogenic - aldolase - albumosuria - alactolyticus - alabamensis - AKTob - Aklomide - akari - aitiology - a-helix - AHCPR - agyric - agophytum - agonists - agglutinogenic - agave - agastria - Agamofilaria - affinitas - aerocystoscopy -
- Service manuals - MBI Corp