Medical term:
osteomalacia
osteomalacia
[os″te-o-mah-la´shah]softening of the bones, resulting from impaired mineralization, with excess accumulation of osteoid, caused by a vitamin D deficiency in adults. A similar condition in children is called rickets. The deficiency may be due to lack of exposure to ultraviolet rays, inadequate intake of vitamin D in the diet, or failure to absorb or utilize vitamin D. There is decalcification of the bones, particularly those of the spine, pelvis, and lower extremities. X-ray examination reveals transverse, fracture-like lines in the affected bones and areas of demineralization in the matrix of the bone. As the bones soften they become bent, flattened, or otherwise deformed. Treatment consists of administration of large daily doses of vitamin D and dietary measures to insure adequate calcium and phosphorus intake. adj., adj osteomala´cic.
antacid-induced osteomalacia osteomalacia in which the combination of low dietary phosphorus intake and chronic excessive consumption of aluminum hydroxide–containing antacids has led to phosphate depletion; characteristics include hypophosphatemia, nephrolithiasis, anorexia, muscle weakness, and bone loss.
anticonvulsant osteomalacia
1. osteomalacia occurring in anticonvulsant rickets of children.
2. anticonvulsant rickets in adults.
hepatic osteomalacia osteomalacia as a complication of cholestatic liver disease, which may lead to severe bone pain and multiple fractures.
oncogenic osteomalacia a type seen in association with usually benign mesenchymal neoplasms. The tumors appear to produce a substance that impairs renal tubular functions and leads to hypophosphatemia. Called also tumor-induced osteomalacia.
puerperal osteomalacia a type resulting from exhaustion of skeletal stores of calcium and phosphorus by repeated pregnancies and lactation.
renal tubular osteomalacia a type resulting from acidosis and hypercalciuria when deficient renal tubular activity has caused inability to produce acid urine or ammonia.
senile osteomalacia softening of bones in old age due to vitamin D deficiency.
tumor-induced osteomalacia oncogenic osteomalacia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
os·te·o·ma·la·ci·a
(os'tē-ō-mă-lā'shē-ă),A disease in adults characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue that has failed to calcify because of lack of vitamin D or renal tubular dysfunction; more common in women than in men, osteomalacia often begins during pregnancy.
Synonym(s): adult rickets, late rickets, rachitis tarda
[osteo- + G. malakia, softness]
Farlex Partner Medical Dictionary © Farlex 2012
osteomalacia
(ŏs′tē-ō-mə-lā′shə, -shē-ə)n.
A bone disease in adults analogous to rickets in children, marked by bone demineralization caused by impaired metabolism or deficiency of vitamin D or phosphorus.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
osteomalacia
Nutritional rickets A condition characterized by softened bones due to poor mineralization occurring in a background of vitamin D deficiency Clinical Weak, deformed, and deformable bone, which in children may be manifest by craniotabes, bowlegs, and knock knees, rachitic rosary, ↓ ventilation, often accompanied by pneumonia, muscular weakness, ↓ appetite, hypocalcemia Treatment Vitamin D. See Osteogenic osteomalacia, Rickets.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
os·te·o·ma·la·ci·a
(os'tē-ō-mă-lā'shē-ă)A disease characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue which has failed to calcify due to lack of vitamin D or renal tubular dysfunction.
Synonym(s): adult rickets, late rickets.
Synonym(s): adult rickets, late rickets.
[osteo- + G. malakia, softness]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
osteomalacia
Bone softening as a result of defective mineralization, usually occurring because of defective calcium absorption from vitamin D deficiency. Osteomalacia is commoner in women than in men. The softened bones may distort or bend under the body weight. The condition is treated with vitamin D.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Osteomalacia
Osteomalacia is a bone disease that occurs in adults and is caused by a prolonged period of vitamin D deficiency.
Mentioned in: Bone X Rays, Laxatives, Vitamin D Deficiency
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
os·te·o·ma·la·ci·a
(os'tē-ō-mă-lā'shē-ă)Disease in adults characterized by a gradual softening and bending of bones with varying severity of pain.
Synonym(s): adult rickets.
Synonym(s): adult rickets.
[osteo- + G. malakia, softness]
Medical Dictionary for the Dental Professions © Farlex 2012
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