Medical term:

pepsinogen


pepsinogen

 [pep-sin´o-jen]
a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pep·sin·o·gen

(pep-sin'ō-jen), [MIM*169700]
A proenzyme or zymogen formed and secreted by the chief cells of the gastric mucosa; the acidity of the gastric juice and pepsin itself remove 44 amino acyl residues from pepsinogen to form active pepsin.
Synonym(s): propepsin
[pepsin + G. -gen, producing]
Farlex Partner Medical Dictionary © Farlex 2012

pepsinogen

(pĕp-sĭn′ə-jən)
n.
The inactive precursor to pepsin, formed in cells of the mucous membrane of the stomach and converted to pepsin by autocatalysis in the presence of hydrochloric acid.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

pep·sin·o·gen

(pep-sin'ŏ-jen)
A proenzyme formed and secreted by the chief cells of the gastric mucosa; the acidity of the gastric juice and pepsin itself remove 42 amino acid residues from pepsinogen to form active pepsin.
Synonym(s): propepsin.
[pepsin + G. -gen, producing]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

pepsinogen

A biochemically inert substance produced by the cells of the stomach lining (gastric mucosa) that is converted to PEPSIN by the action of hydrochloric acid.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

pepsinogen

a precursor of PEPSIN in the vertebrate stomach which, in the presence of hydrochloric acid (also secreted by the OXYNTIC CELLS in the stomach wall), gives rise to more active pepsin, which itself activates pepsinogen. The reaction is thus auto catalytic.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

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