Medical term:

spirem

spi·rem

, spireme (spī'rem, spī'rēm),

Term formerly applied to the first stage of mitosis or meiosis (prophase) during which extended chromosome filaments have the appearance of a loose ball of yarn, on the incorrect supposition that the filaments were continuous and later broke apart to form individual chromosomes.

[G. speirēma, a coil 1]

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