Medical term:
thrombase
thrombin
[throm´bin]1. the activated form of coagulation factor II (prothrombin), which catalyzes the conversion of fibrinogen to fibrin.
2. a preparation of this compound prepared from prothrombin of bovine origin, used as a topical hemostatic.
thrombin time (TT) the time required for plasma fibrinogen to form thrombin: exogenous thrombin is added to citrated plasma and the time to clot formation is measured. Prolonged TT is seen with abnormalities of fibrinogen and in the presence of heparin or degradation products of fibrin or fibrinogen.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
throm·bin
(throm'bin),1. An enzyme (proteinase), formed in shed blood, that converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase (factor Xa, another proteinase).
2. A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting of whole blood, plasma, or a fibrinogen solution; used as a topical hemostatic for capillary bleeding with or without fibrin foam in general and plastic surgical procedures.
Synonym(s): factor IIa, fibrinogenase, thrombase, thrombosin
Farlex Partner Medical Dictionary © Farlex 2012
thrombin
(thrŏm′bĭn)n.
A protease in blood that facilitates blood clotting by converting fibrinogen to fibrin.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
thrombin
Hematology A key clot promoting enzyme that converts fibrinogen to fibrin and protects against fibrinolysis by activating thrombin-activatable fibrinolysis inhibitor. See Fibrin, Fibrinolysis, TAFI.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
throm·bin
(throm'bin)1. An enzyme (proteinase), formed in shed blood, that converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase (factor Xa, another proteinase).
2. A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting of whole blood, plasma, or a fibrinogen solution; used as a topical hemostatic for capillary bleeding with or without fibrin foam in general and plastic surgical procedures.
Synonym(s): factor IIa.
Synonym(s): factor IIa.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
thrombin
An enzyme in the blood that converts fibrinogen to fibrin, thus forming a blood clot.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
thrombin
see BLOOD CLOTTING.Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
Thrombin
Thrombin is a protein produced by the body. It is a specific clotting factor that plays an important role in the blood clotting process.
Mentioned in: Anticoagulant and Antiplatelet Drugs, Fibrinogen Test, Prothrombin Time
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
throm·bin
(throm'bin)1. An enzyme (proteinase), formed in shed blood, which converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase.
2. A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting; used as a topical hemostatic for capillary bleeding in general and plastic surgical procedures.
Synonym(s): factor IIa.
Synonym(s): factor IIa.
Medical Dictionary for the Dental Professions © Farlex 2012
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