Medical term:
aldosterone
aldosterone
[al-dos´ter-ōn, al´do-ster-ōn″]the main mineralocorticoid hormone secreted by the adrenal cortex, the principal biological activity of which is the regulation of electrolyte and water balance by promoting the retention of sodium (and, therefore, of water) and the excretion of potassium; the retention of water induces an increase in plasma volume and an increase in blood pressure. Its secretion is stimulated by angiotensin II.
aldosterone antagonist a compound that blocks the action of aldosterone; the group includes potassium sparing diuretics such as spironolactone that compete with aldosterone for receptor sites, thus blocking the aldosterone-dependent exchange of sodium and potassium in the distal tubule.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
al·dos·ter·one
(al-dos'tĕr-ōn), Avoid the mispronunciation aldoster'one.A mineralocorticoid hormone produced by the zona glomerulosa of the adrenal cortex; its major action is to facilitate potassium exchange for sodium in the distal renal tubule, causing sodium reabsorption and potassium and hydrogen loss; the principal mineralocorticoid. It exists in equilibrium with the aldehyde form.
Farlex Partner Medical Dictionary © Farlex 2012
aldosterone
(ăl-dŏs′tə-rōn′)n.
A steroid hormone that is produced by the adrenal cortex and regulates salt balance, blood volume, and blood pressure in the body.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
aldosterone
An adrenocortical mineralocorticoid that controls electrolyte and water homeostasis by regulating reabsorption of Na+ and Cl– in exchange for K+ and H+, and which maintains blood pressure and blood volume. Aldosterone secretion is controlled by the RAA system and by concentrations of K+ in the circulation, which if increased evokes secretion of aldosterone. Reduced Na+ evokes renin release, which stimulates aldosterone secretion; aldosterone may be measured when evaluating hypertension.Increased in
Adrenocortical adenoma or carcinoma, bilateral adrenal hyperplasia, renovascular hypertension, liver disease, congestive heart failure, cirrhosis, nephrotic syndrome, pregnancy (3rd trimester).
Decreased in
Primary hypoaldosteronism, salt-losing syndrome, eclampsia/toxemia of pregnancy, Addison’s disease (chronic adrenal insufficiency).
Ref range
• Serum, ≤ 20 mg/dL.
• Urine, ≤ 20mg/24 hours.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
aldosterone
Endocrinology An adrenocortical mineralocorticoid hormone that controls the body's electrolyte and water homeostasis by regulating reabsorption of Na+ and Cl– in exchange for K+ and H+ ions, and maintaining BP and blood volume; aldosterone secretion is controlled by the RAA system and by concentrations of K+ in the circulation, which if ↑, evokes secretion of aldosterone; ↓ Na+ evokes renin release, which stimulates aldosterone secretion; aldosterone may be measured when evaluating HTN; aldosterone is ↑ in adrenocortical adenoma or CA, bilateral adrenal hyperplasia, renovascular HTN, liver disease, CHF, cirrhosis, nephrotic syndrome, pregnancy–3rd trimester; it is ↓ in 1º hypoaldosteronism, salt-losing syndrome, toxemia of pregnancy, Addison's disease Ref range Serum, ≤ 20 mg/dL; ≤ 20mg/24hrs, urine. See Hypertension, Pseudoaldosterone, Timed collections.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
al·dos·ter·one
(al-dos'tĕr-ōn)A hormone produced by the cortex of the suprarenal gland; its major action is to facilitate potassium exchange for sodium in the distal renal tubule, causing sodium reabsorption and potassium and hydrogen loss; the principal mineralocorticoid.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
aldosterone
One of the STEROID hormones produced by the outer part of the adrenal gland. Aldosterone is concerned with the control of salt and water loss in the urine.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
aldosterone
a hormone of the cortex of the ADRENAL GLAND. It is responsible for the relative concentration of sodium and potassium ions in the body. It promotes the reabsorption of sodium ions from the ascending limb of the LOOP OF HENLE in the kidney, with the elimination of potassium ions, and increases the uptake of sodium ions by the alimentary canal. The concentration of sodium ions in the blood thus rises and potassium ions fall, making possible the ionic regulation of body fluids (see SODIUM PUMP).Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
Aldosterone
A hormone secreted by the adrenal glands that is important for maintaining salt and water balance in the body.
Mentioned in: Congenital Adrenal Hyperplasia
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
al·dos·ter·one
(al-dos'tĕr-ōn) Avoid the mispronunciation aldoster'one.Mineralocorticoid hormone produced by the zona glomerulosa of the cortex of the suprarenal gland that facilitates potassium exchange for sodium in the distal renal tubule, causing sodium reabsorption and potassium and hydrogen loss.
Medical Dictionary for the Dental Professions © Farlex 2012
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