Medical term:

pseudocholinesterase


bu·tyr·o·cho·lin·es·ter·ase

(byū'tir-ō-kō'lin-es'ter-ās),
Pseudocholinesterase or plasma cholinesterase.
See also: cholinesterase.
Synonym(s): butyrylcholine esterase, pseudocholinesterase
Farlex Partner Medical Dictionary © Farlex 2012

BCHE

A gene on chromosome 3q26.1-2 that encodes butyrylcholinesterase, which has a broad substrate spectrum. It contributes to inactivation of the neurotransmitter acetylcholine and can degrade neurotoxic organophosphate esters.
 
Molecular pathology
Mutant alleles at BCHE are responsible for suxamethonium sensitivity.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

pseudocholinesterase

A liver and plasma enzyme that rapidly metabolizes succinylcholine, a short-acting–5-10 mins–neuromuscular anesthetic, thereby controlling its duration of action; some people have congenital PChe variants, in which neuromuscular block is prolonged with usual doses of succinylcholine–and identified by determining the 'dibucaine' number; PChe activity may be ↓ in various acquired conditions–eg, liver disease–hepatitis, cirrhosis, metastasis, malnutrition, acute infections, anemia, MIs, CA, pregnancy, cytotoxic drugs, acetylcholinesterase inhibitors, dermatomyositis. See Dibucaine number.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

plas·ma chol·ine·ste·rase

(plaz'mă kō'lin-es'tĕr-ās)
A type of cholinesterase found in plasma.
See also: fluoride number
Synonym(s): butyrylcholinesterase, pseudocholinesterase.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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