Medical term:
trimetrexate
trimetrexate
[tri″-mĕ-trek´sāt]a folic acid antagonist structurally related to methotrexate, used as the glucuronate salt, in combination with leucovorin, to treat Pneumocystis carinii pneumonia in acquired immunodeficiency syndrome, administered intravenously.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
trimetrexate
An inhibitor of the enzyme DIHYDROFOLATE REDUCTASE. It is used to treat Pneumocystis carinii pneumonia in people with AIDS. A brand name is Neutrexin.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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