Medical term:

tyrosine

[ti´ro-sēn]

a naturally occurring, nonessential amino acid present in most proteins and synthesized metabolically from phenylalanine. It is a precursor of melanin, catecholamines, and thyroid hormones.

ty·ro·sine (Tyr, Y),

(tī'rō-sēn, -sin),

2-Amino-3-(4-hydroxyphenyl)propionic acid; 3-(4-hydroxyphenyl)alanine; the l-isomer is an α-amino acid present in most proteins.

Farlex Partner Medical Dictionary © Farlex 2012

tyrosine

(tī′rə-sēn′)

A nonessential amino acid, C₉H₁₁NO₃, that is produced in the body from phenylalanine and is a precursor of melanin and of several neurotransmitters and hormones, such as epinephrine and thyroxine.

ty·ro·sine

(Tyr, Y) (tī'rō-sēn)

An α-amino acid present in most proteins.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

tyrosine

The AMINO ACID 4-hydroxyphenylalanine. This is one of the 20 amino acids that are incorporated into protein.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Fig. 308 Tyrosine . Molecular structure.

tyrosine (Y, Tyr)

one of the 20 AMINO ACIDS common in PROTEINS. It has a polar ‘R’ group structure and is soluble in water. See Fig. 308 . The ISOELECTRIC POINT of tyrosine is 5.7.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Tyrosine

A protein building block found in a wide variety of foods that is used by the body to make melanin.

Mentioned in: Albinism

ty·ro·sine

(Tyr) (tī'rō-sēn)

An α-amino acid present in most proteins.

Medical Dictionary for the Dental Professions © Farlex 2012

tyrosinemia

[ti″ro-sĭ-ne´me-ah]

an aminoacidopathy consisting of defective metabolism of tyrosine and its buildup in the body, as well as urinary excretion of related metabolites. Several forms exist: Type I is an autosomal recessive trait with an acute form that is usually fatal in infancy and a chronic form characterized by chronic liver and kidney disease, rickets, and death in childhood. Type II is an oculocutaneous syndrome with crystallization of accumulated tyrosine in the epidermis as palmoplantar hyperkeratoses and in the corneas as herpetiform ulcers, often accompanied by mental retardation.

ty·ro·si·ne·mi·a

(tī'rō-si-nē'mē-ă), [MIM*276600, *276700, and *276710]

A group of autosomal recessively inherited disorders of tyrosine metabolism associated with elevated blood concentration of tyrosine, and enhanced urinary excretion of tyrosine and tyrosyl compounds. Type I tyrosinemia, due to deficiency of fumarylacetoacetase (FAH), is characterized by hepatosplenomegaly, nodular liver cirrhosis, multiple renal tubular reabsorptive defects, and vitamin D-resistant rickets; caused by mutation in the FAH gene on chromosome 15q. Type II tyrosinemia, due to deficiency of tyrosine aminotransferase (TAT), is characterized by corneal ulcers and keratosis of digits, palms, and soles; caused by mutation in the TAT gene on 16q. Type III tyrosinemia is associated with intermittent ataxia and drowsiness without liver dysfunction and is due to 4-hydroxy-phenylpyruvate dioxygenase (4HPPD) deficiency.

Synonym(s): hypertyrosinemia

[tyrosine + G. haima, blood]

ty·ro·si·ne·mi·a

(tī'rō-si-nē'mē-ă) [MIM*276600, *276700, and *276710]

Inherited disorders of tyrosine metabolism associated with elevated blood concentration of tyrosine and enhanced urinary excretion of tyrosine and tyrosyl compounds.

[tyrosine + G. haima, blood]

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